Development of Imaging Mass Spectrometry

Imaging with mass spectrometry.

[Imaging mass spectrometry].

Matrix-assisted laser desorption/ionization (MALDI)-imaging mass spectrometry (IMS) enables the visualization of the distribution of a range of biomolecules that have varied structures in the cells and tissue sections. This emerging imaging technique was initially developed as a tool for protein imaging, but recently it is increasingly being used for the imaging of small organic molecules. IMS ...

Development and Application of Software Tools for Mass Spectrometry Imaging

Källback, P. 2017. Development and Application of Software Tools for Mass Spectrometry Imaging. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Pharmacy 234. 66 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-513-0040-5. Mass spectrometry imaging (MSI) has been extensively used to produce qualitative maps of distributions of proteins, peptides, lipids, neur...

Monitoring mouse prostate development by profiling and imaging mass spectrometry.

Mass spectrometry-based tissue profiling and imaging are technologies that allow identification and visualization of protein signals directly on thin sections cut from fresh frozen tissue specimens. These technologies were utilized to evaluate protein expression profiles in the normal mouse prostate during development (1-5 weeks of age), at sexual maturation (6 weeks of age), and in adult prost...

A mass spectrometry primer for mass spectrometry imaging.

Mass spectrometry imaging (MSI), a rapidly growing subfield of chemical imaging, employs mass spectrometry (MS) technologies to create single- and multi-dimensional localization maps for a variety of atoms and molecules. Complimentary to other imaging approaches, MSI provides high chemical specificity and broad analyte coverage. This powerful analytical toolset is capable of measuring the distr...